Covid: ADE May Account for Severity of Cases in Wuhan Province 

In other words, vaccinated people are going to have more severe disease in the next wave, unless they stock up on vitamin D and zinc.   And they’ve known about ADE in coronaviruses since around 2012.

Abstract

One of the most perplexing questions regarding the current COVID-19 coronavirus epidemic is the discrepancy between the severity of cases observed in the Hubei province of China and those occurring elsewhere in the world. One possible answer is antibody dependent enhancement (ADE) of SARS-CoV-2 due to prior exposure to other coronaviruses. ADE modulates the immune response and can elicit sustained inflammation, lymphopenia, and/or cytokine storm, one or all of which have been documented in severe cases and deaths. ADE also requires prior exposure to similar antigenic epitopes, presumably circulating in local viruses, making it a possible explanation for the observed geographic limitation of severe cases and deaths….

    https://www.sciencedirect.com/science/article/pii/S1286457920300344?via%3Dihub

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