“The aluminium content of brain tissues from donors with a diagnosis of ASD [Autism] was extremely high…the mean aluminium content for each lobe across all 5 individuals was towards the higher end of all previous (historical) measurements of brain aluminium content, including iatrogenic disorders such as dialysis encephalopathy …We recorded some of the highest values for brain aluminium content ever measured in healthy or diseased tissues in these male ASD donors…Why, for example would a 15 year old boy have such a high content of aluminium in their brain tissues?”
“Perhaps equally important if not more important were the microscopy studies. The microscopy studies enable us to identify where the aluminum was in the brain tissue. When we looked at our brains of people with a diagnosis of autism, we found something completely different and something we’ve never seen before as yet in any other set of human brains. We found that the majority of aluminum was actually inside cells, intracellular. Some of it was inside neurons, but actually the majority of it was inside non-neuronal cell populations. So we found that these cells were heavily loaded with aluminum. We also saw evidence that cells in the lymph and in the blood were passing into the brain, so they were carrying with them a cargo of aluminum from the body into the brain. This is the first time in any human brain tissue we have seen this so this is a standout and as yet unique observation in autism. For myself, it very much implicates aluminum in the etiology of autism. That doesn’t mean aluminum causes it, but it’s almost certainly playing a role in the disease.”
Aluminium in brain tissue in autism
Autism spectrum disorder is a neurodevelopmental disorder of unknown aetiology. It is suggested to involve both genetic susceptibility and environmental factors including in the latter environmental toxins. Human exposure to the environmental toxin aluminium has been linked, if tentatively, to autism spectrum disorder. Herein we have used transversely heated graphite furnace atomic absorption spectrometry to measure, for the first time, the aluminium content of brain tissue from donors with a diagnosis of autism. We have also used an aluminium-selective fluor to identify aluminium in brain tissue using fluorescence microscopy. The aluminium content of brain tissue in autism was consistently high. The mean (standard deviation) aluminium content across all 5 individuals for each lobe were 3.82(5.42), 2.30(2.00), 2.79(4.05) and 3.82(5.17) μg/g dry wt. for the occipital, frontal, temporal and parietal lobes respectively. These are some of the highest values for aluminium in human brain tissue yet recorded and one has to question why, for example, the aluminium content of the occipital lobe of a 15 year old boy would be 8.74 (11.59) μg/g dry wt.? Aluminium-selective fluorescence microscopy was used to identify aluminium in brain tissue in 10 donors. While aluminium was imaged associated with neurones it appeared to be present intracellularly in microglia-like cells and other inflammatory non-neuronal cells in the meninges, vasculature, grey and white matter. The pre-eminence of intracellular aluminium associated with non-neuronal cells was a standout observation in autism brain tissue and may offer clues as to both the origin of the brain aluminium as well as a putative role in autism spectrum disorder.
New study: Massive Aluminum levels in Autism brains, is this the smoking gun for vaccines?