COVID-19 Research: A major collaboration of international experts from various medical, genomic and biological fields lead by Northeastern’s Center for Complex Network Science Research has identified that the SARS-Cov-2 coronavirus is able to target 332 human proteins and also has a variety of binding sites, not just the four that was initially discovered including ACE-2 receptors.
The new research indicates that the SARS-CoV-2 coronavirus can be described as the potent virus ever known to mankind. With more details of the structure of the new virus genome and also the way it interacts with the various human proteins, the researchers have also identified 40 new drugs that could be repurposed for usage to treat COVID-19.
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The study findings, come from a modeling tool for infection dynamics based on network science utilizing complex math, physics, and computing. https://www.biorxiv.org/content/10.1101/2020.03.22.002386v1
The new toolset mapped the way proteins within human cells behave after a cell is hijacked with SARS-CoV-2, the new coronavirus that causes the COVID-19 illness.
Dr Albert-László Barabási, Robert Gray Dodge Professor of Network Science and University Distinguished Professor of physics at Northeastern told Thailand Medical News, “We have prioritized many more drugs, but there are 40 that we are actually trying to move forward.” https://covid.barabasilab.com/2020/04/network-based-embedding-of-all-human.html….