Traumatic stress experienced by mice early in life has epigenetic repercussions that reverberate across multiple generations.
The unhealthy behavior exhibited by mice who were subjected to emotional stress during the early post-natal stage was passed down to their offspring, according to a new study by researchers at the University of Zurich (UZH). Because previous studies have identified a similar inheritance process in humans, researchers are searching for ways to counteract these epigenetic effects.
Previous researchers have theorized that behaviors induced by traumatic experiences could pass between humans and their offspring through epigenetic modifications—that is, changes that regulate gene expression without changing the DNA sequence of an organism. These theories were based on only on observations of families with a history of behavioral disorders and groups who were disposed to post-traumatic stress disorder (PTSD), so the link between behavior and biology had not been extensively explored.
UZH researchers attempted to understand this link by testing whether unhealthy behavior that resulted from traumatic experiences could be passed from one generation of mice to the next. The researchers choose to work with mice instead of humans; because social interaction and learned behavior is so robust, the causes for unhealthy human behavior are difficult to separate between biological and social factors.Researchers subjected a cohort of male mice to unpredictable maternal separation and unpredictable maternal stress (MSUS) during the first two weeks of post-natal life. As adults, these mice were subjected to a series of well-established tasks and behavioral markers that detected social incompetency, impulsivity, and depression. These stressed males were then bred with normal females, who were left raise their pups under normal, non-stressful, conditions. When these second-generation pups became adults, they showed the similar unhealthy behavioral patterns to their fathers. Since the males had no contact with the pups, the results suggest that the behavior was passed down through epigenetic factors. …
But now that they KNOW it’s not nice to traumatize newborn babies they’ll surely put a stop to it right? Riiiiiight. This is where normal people’s capacity for understanding hits a brick wall. Medicine, like the rest of the establishment, is controlled at the top by control freak psychopaths. Get used to it.