Cancer Research Fraud Endemic

Cancer Research False Claims by Vera Sharav

A committee of the National Academy of Sciences heard testimony about the tenfold increase during the last decade, in the number of scientific journal articles that had to be retracted.

But that number may obscure the far greater number of unsupportable published reports in so-called peer reviewed academic journals that are never retracted.

A report in NATURE, by Glenn Begley (former head of cancer research at Amgen) and Lee Ellis (surgical oncologist at MD Anderson), Drug development: Raise standards for preclinical cancer research describes the effort of 100 Amgen scientists to replicate the results claimed by the authors of 53 widely cited landmark cancer research papers.

The Amgen scientists were astonished to find that they were able to replicate only 6 (11%) of the 53 published conclusions.

“It was shocking,” said Begley, now senior vice president of privately held biotechnology company TetraLogic, which develops cancer drugs. “These are the studies the pharmaceutical industry relies on to identify new targets for drug development. But if you’re going to place a $1 million or $2 million or $5 million bet on an observation, you need to be sure it’s true. As we tried to reproduce these papers we became convinced you can’t take anything at face value.”

So, it is cancer research academics–not industry scientists–who are responsible for polluting the scientific literature with false “positive” claimed findings. Indeed, even when the academic got the result he published only once–after attempting, but failing, six times to replicate his own finding–he nevertheless submitted his unsupportable finding for publication.

Some authors required the Amgen scientists sign a confidentiality agreement barring them from disclosing data at odds with the original findings. “The world will never know” which 47 studies — many of them highly cited — are apparently wrong, Begley said. Such a legal shield protects fraud and fraudsters.

How can one justify a public expenditure of more than $4.9 billion annually for cancer research whose integrity cannot be relied upon?

Full article at http://www.ahrp.org/cms/content/view/839/150/

Just In Time – or not

There are two types of “Prepper”. One is the survivalist, hunker-down, zero-sum, me-against-them, guns and ammo crowd. The other is visionary, co-operative, community oriented  and engaged ( see http://www.prepper.org/ ). Both are getting ready for what seems an obvious end-game to the bankster coup being perpetrated on the world’s peoples. Here’s a practical look at one scenario regarding our industrial distribution network.

Read This First Before You Decide That Preppers Are Crazy

from  http://theeconomiccollapseblog.com

The truth is that our “just in time” inventory and delivery systems leave us incredibly vulnerable to a nationwide disaster.

You see, it is very expensive to hold and store inventory, so most manufacturers and retailers rely on a continual flow of deliveries that are scheduled to arrive “just in time”, and this significantly reduces their operating expenses.

This is considered to be good business practice for manufacturers and retailers, but it also means that if there was a major nationwide transportation disruption that our economic system would grind to a halt almost immediately.

Once store shelves are picked clean, they would not be able to be replenished until trucks could get back on the road.  In the event of a major nationwide disaster, that could be quite a while.

If something caused the trucks to stop running, life in America would immediately start changing.

So exactly what would that look like?

The following is an excerpt from the report mentioned above put out by the American Trucker Associations entitled “When Trucks Stop, America Stops“….

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A Timeline Showing the Deterioration of Major Industries Following a Truck Stoppage

The first 24 hours

• Delivery of medical supplies to the affected area will cease.
• Hospitals will run out of basic supplies such as syringes and catheters within hours. Radiopharmaceuticals will deteriorate and become unusable.
• Service stations will begin to run out of fuel.
• Manufacturers using just-in-time manufacturing will develop component shortages.
• U.S. mail and other package delivery will cease.

Within one day

• Food shortages will begin to develop.
• Automobile fuel availability and delivery will dwindle, leading to skyrocketing prices and long lines at the gas pumps.
• Without manufacturing components and trucks for product delivery,
assembly lines will shut down, putting thousands out of work.

Within two to three days

• Food shortages will escalate, especially in the face of hoarding and consumer panic.
• Supplies of essentials—such as bottled water, powdered milk, and
canned meat—at major retailers will disappear.
• ATMs will run out of cash and banks will be unable to process
transactions.
• Service stations will completely run out of fuel for autos and trucks.
• Garbage will start piling up in urban and suburban areas.
• Container ships will sit idle in ports and rail transport will be disrupted, eventually coming to a standstill.

Within a week

• Automobile travel will cease due to the lack of fuel. Without autos and busses, many people will not be able to get to work, shop for groceries, or access medical care.
• Hospitals will begin to exhaust oxygen supplies.

Within two weeks

• The nation’s clean water supply will begin to run dry.

Within four weeks

• The nation will exhaust its clean water supply and water will be safe for drinking only after boiling. As a result gastrointestinal illnesses will increase, further taxing an already weakened health care system.

This timeline presents only the primary effects of a freeze on truck travel. Secondary effects must be considered as well, such as inability to maintain telecommunications service, reduced law enforcement, increased crime, increased illness and injury, higher death rates, and likely, civil unrest.

Full article at http://theeconomiccollapseblog.com/archives/read-this-first-before-you-decide-that-preppers-are-crazy